Downsize Nightly Nightburn is a truly unique formula designed to aid in steady weight loss. It can be used to augment nearly any weight loss program. Downsize Nightly is carefully formulated to help your body increase its metabolism of stubborn fat during your prime recovery period, while you sleep. It deepens your sleep and improves dopamine. Additionally, two capsules at bedtime help reduce the anxiety and stress that can wreck a peaceful night’s sleep.